Laboratory：Laboratory of Molecular Metabolic Regulation

Research direction: Plasma lipid transport and hepatic lipid metabolism

Paper：

1. Huang D*, Xu B*, Liu L*, Wu L, Zhu Y, Ghanbarpour A, Wang Y, Chen FJ, Lyu J, Hu Y, Kang Y, Zhou W, Wang X, Ding W, Li X, Jiang Z, Chen J, Zhang X, Zhou H, Li JZ, Guo C, Zheng W, Zhang X, Li P, Melia T, Reinisch K, Chen XW. TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis. Cell Metab. 2021 Aug 3; 33 (8):1655-1670.

2. Wu L, Liu L, Xu B, Huang D, Chen XW. In vitro and in vivo assay of the ER lipid scramblase TMEM41B. STAR Protoc. 2022 Apr 19;3(2):101333.

3. Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW. Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans. Cell Metab. 2021 Feb 2; 33 (2):350-366.

4. Shi F, Wang Y, Huang D, Liang Y, Liang N, Chen X, Gao G. Computational Assessment of the Regulation-Modulating Potential for Noncoding Variants. Genomics, Proteomics & Bioinformatics. 2021.