Professor

Vice Dean, Dept. Biomedical Engineering

National Outstanding Young Scholar

Biography

Dr. Peng Xi is a full professor in College of Future Technology, Peking University, China. His research interest is on the development of optical super-resolution microscopy techniques. He has been awarded the National Outstanding Young Scholar. He has published over 80 scientific journal papers on peer-reviewed journals including Nature, Nature Methods, etc., and delivered over 30 keynote/invited talks on international conferences hosted by SPIE and OSA. He is a Senior member of Optica. He was the chair of OSA Imaging Optical Design Technical Group (2016-2019). He is on the editorial board of 5 SCI-indexed journals such as Light: Science and Applications, and Advanced Photonics.

Courses

n Biomedical Image Processing (UG, 3 credits)

n Biomedical Optics and Applications (UG, 3 credits)

Education

n BE 1998 Opto-electronic Engineering, Shanxi University

n Ph. D.  2003 Optical Engineering, Chinese Academy of Sciences (Supervisor: Prof. Changhe Zhou)

Experience

n 2003. 8 – 2004.12  Research Associate, Department of Electrical and Electronic Engineering, Hong Kong University of Science and Technology, Kowloon, Hong Kong (Advisor: Prof. Jianan Q. Qu)

n 2005. 2 – 2006.11  Research Associate, Bindley Bioscience Center, Purdue University, West Lafayette, IN, USA. (Advisor: Prof. J. Paul Robinson)  

n 2006. 12 – 2007.12  Research Associate, Department of Chemistry, Michigan State University, East Lansing, MI, USA. (Advisor: Prof. Marcos Dantus)

n 2008. 1 – 2009.11 Associate Professor,  School of Life Sciences and Biotechnology,  Shanghai Jiao-Tong University, Shanghai, China

n 2009. 12 – 2021.1 Associate Professor, Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, China

n 2021. 4 – now Professor, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China

Projects:

n 2021.1-2024.12 Principal Investigator, National Natural Science Foundation of China (No. 62025501)

Title: Super-resolution fluorescence microscopy (RMB 4,000,000)

n 2020. 1 – 2023.12 Principal Investigator, National Natural Science Foundation of China (No. 31971376)

Title: Real-time large field-of-view three-dimensional lensfree microscopy (RMB 600,000)

Representative publications:

1. Karl Zhanghao*, Wenhui Liu, Meiqi Li, Zihan Wu, Xiao Wang, Xingye Chen, Chunyan Shan, Haoqian Wang, Xiaowei Chen, Qionghai Dai, Peng Xi*, Dayong Jin*, High-dimensional super-resolution imaging reveals heterogeneity and dynamics of subcellular lipid membranes, Nature Communications, 11: 5890 (2020).

2. X. Yang, Z. Yang, Z. Wu, Y. He, C. Shan, P. Chai, C. Ma, M. Tian, J. Teng, D. Jin, W. Yan, P. Das, J. Qu*, P. Xi*, “Mitochondrial dynamics quantitatively revealed by sted nanoscopy with an enhanced squaraine variant probe” Nature Communications 11:3699 (2020).

3. Jiang, S., Guan, M., Wu, J., Fang, G., Xu, X., Jin, D., Liu, Z., Shi, K., Bai, F., Wang, S. and Xi, P., 2020. Frequency-domain diagonal extension imaging. Advanced Photonics, 2(3), p.036005.

4. L. Chen, M. Wang, X. Zhang, M. Zhang, Y. Hu, Z. Shi, P. Xi*, J. Gao*, “Group-sparsity-based super-resolution dipole orientation mapping (GS-SDOM),” IEEE Transactions on medical imaging 38, 2687-2694 (2019).

5. K. Zhanghao, X. Chen, M. Li, Y. Liu, W. Liu, S. Luo, X. Wang, K. Zhao, A. Lai, C. Shan, H. Xie, Y. Zhang, X. Li, Q. Dai, and P. Xi*, “Super-resolution Imaging of Fluorescent Dipoles by Polarized Structured Illumination Microscopy,” Nature Communications 10, 4694 (2019).

6. A. Lal, C. Shan, K. Zhao, W. Liu, X. Huang, W. Zong, L. Chen, P. Xi*, A frequency domain SIM reconstruction algorithm using reduced number of images. IEEE Transactions on Image Processing 27(9), 4555-4570 (2018).

7. D. Jin*, P. Xi*, B. Wang, L. Zhang, J. Enderlein*, A. M. Oijen*, “Nanoparticles for super-resolution microscopy and single-molecule tracking”, Nature Methods, 15, 415-423 (2018).

8. Y. Liu, Y. Lu*, X. Yang, X. Zheng, S. Wen, F. Wang, X. Vidal, T. Zhao, D. Liu, Z. Zhou, C. Ma, J. Zhou, J. Piper, P. Xi*, and D. Jin*, “Amplified stimulated emission in upconversion nanoparticles for super resolution nanoscopy,” Nature 543, 229-233 (2017).

9. K. Zhanghao, L. Chen, X. Yang, M. Wang, Z. Jing, H. Han, M. Q. Zhang, D. Jin*, J. Gao*, P. Xi*, “Super-resolution dipole orientation mapping via polarization demodulation”, Light: Science and Applications 5, e16166 (2016). [2016 Impact factor: 13.6] This paper has been highlighted by Nature Methods.

10. X. Yang, H. Xie, E. Alonas, Y. Liu, X. Chen, Q. Ren, P. J. Santangelo, P. Xi*, and D. Jin, “Mirror enhanced super-resolution microscopy”, Light: Science and Applications 5, e16134 (2016). [2016 Impact factor: 13.6] This paper has been highlighted by Nature Photonics.