Professor

Professor, Department of Biomedical Engineering

Associate Dean, Faculty of Informatioand Engineering, Peking University

Chinese Ministry of EducatioAppointed Chang-Jiang Distinguished Professor

Leader of molecular imaging InnovatioGroup, National Natural Science Foundatioof China

National Outstanding Young Scientist Award

Principal scientist, National Key Initiative for Scientific Instrumentation

Principal scientist, National Key Basic Research Project (973 Project)

Director of the Institute of Biomedical Engineering, Peking University Shenzhen Graduate School

Leader of Facility 1 of "National Multimodal and Cross-Scale Biomedical Imaging Facility" at Peking University

Fellow, AmericaInstitute of Medical and Biological Engineering（AIMBE）

Fellow, International Society for Optics and Photonics (SPIE)

Biography

Professor ReQiushi focuses othe research field of “multimodal molecular medical imaging innovations plus artificial intelligence,” targeting early diagnosis and functional imaging of major diseases such as cancer, cardiovascular and cerebrovascular disorders, and neurological conditions. His research spans molecular medical imaging technology and equipment, visioscience and diagnostic techniques, and laser & photonic biomedicine.  

Building oa series of independently developed multimodal molecular imaging systems ihis laboratory and integrating AI technologies, he has worked closely with multidisciplinary clinicians to conduct pioneering translational research and clinical applications imultimodal molecular imaging. These efforts have incubated China’s first 64-slice PET/CT, next-generatiofully digital PET/CT, whole-body PET/CT, a small-animal five-modality imaging system, a multimodal visual-functioimaging analyzer, a multifunctional fully automated fundus camera, and aophthalmic optical coherence tomography (OCT) device, among other high-performance medical imaging instruments.  

Among them, the multimodal visual-functioimaging system combines multispectral imaging, laser-speckle imaging, adaptive-optics imaging, dynamic pupillary-response imaging analysis, and eye-movement imaging analysis. It enables objective quantificatioof retinal metabolic function, local blood-flow dynamics, retinal vessel wall and lumediameter, pupillary responses under various conditions, and eye-movement patterns during visual tasks, providing new tools and methods for investigating the mechanisms underlying eye diseases and for early diagnosis and monitoring of neurological disorders.  

To date, Professor Rehas published over 300 academic papers, obtained 2 U.S. patents, 3 international patents, and more tha100 domestic patents.

Courses

nGraduate students: Laser Medicine (Elective, 3 credits)

Education

nBE 1984 Department of Optical Engineering, Huazhong University of Science and Technology

nM. Sc 1987 Department of Electrical Engineering, Ohio State University

nPh. D.  1990 Department of Electrical Engineering, Ohio State University

Experience

n1991-1994 Assistant Professor, Department of Biomedical Engineering, University of Miami

n2002-2009 Professor, Department of Biomedical Engineering, Shanghai Jiaotong University

n2009-present Professor, Department of Biomedical Engineering, School of Engineering, Peking University

Projects:

n01/2016 – 12/2021 Group Leader and Lead PI, Group InnovatioAward iMulti-modality Molecular Imaging, Natural Science Foundatioof China (NSFC)

10/2011 – 09/2016 Chief Scientist and Principal Investigator, National Key Initiative for Scientific Instrumentation

Title: Research and Development of Multi-Modality (CT, PET, SPECT, FMT) Molecular Imaging System for Animal Research

Founding Agencies: China Ministry Of Science and Technology

Amount: ￥55.1million

n01/2011 – 10/2015 Chief Scientist and Principle Investigator, National Key Basic Research Project (973 Project):

Title : Visual Prosthesis for Blind People and Related Key Technologies

Founding Agency: Chinese Ministry of Science and Technology

Amount: ￥26.8million

n01/2008 – 12/2012 Principal Investigator, International Expert Exchange for InnovatioiScience and Technology (111 Program)

Title: Advanced Minimal Invasive Medical Technology Development

Founding Agencies:  State Administratioof ForeigExperts Affairs and

Ministry of Educatioof China

Amount: ￥4.5million

n12/2007 – 11/2010  Principal Investigator, National Key Technologies R&D Program

Title: Distributed Wireless Biosensor Technologies for Emergency Care

Founding Agency: Chinese Ministry of Science and Technology

Amount: ￥2million

n11/2005 – 10/2010 Chief Scientist and Principle Investigator, National Key Basic Research Project (973 Project):

Title : Visual Prosthesis for Blind People and Related Key Technologies

Founding Agency: Chinese Ministry of Science and Technology

Amount: ￥30million

n11/2005 – 10/2009 National Outstanding Young Scientist Award

Title: InvestigatiooBasic Mechanism and Key Technologies for Visual Prosthesis

Funding Agency: China Natural Science Foundation

Amount: ￥1million

n10/2005 – 09/2007 Principle Investigator

Title: Laser Tissue Interactioand Its Applications iMinimal Invasive Surgery

Founding Agency: Shanghai Commissiofor Science and Technology

Amount: ￥900,000.00

n09/2004 – 08/2006 Principle Investigator

Title: Optical-Electrical Micro-System (OEMS) for Implantable Visual Prosthesis

Founding Agency: Shanghai Commissiofor Science and Technology

Amount: ￥600,000.00

n12/2003 – 11/2006 Principle Investigator

Title: Laser Hyper-polarized Noble Gas Enhanced MR Imaging for Lung Diseases

Founding Agency: Shanghai Commissiofor Science and Technology

Amount: ￥800,000.00

n01/2004 – 12/2006 Principal Investigator

Title: Non-Invasive Endo-Confocal Imaging for Early Detectioof Cell Malformation

Founding Agency: Chinese Natural Science Foundation

Amount: ￥260,000.00

Representative publications:

1. Guocheng Xiao, Mei Ge, Guoqing Qiao, Shuyu Liu, Na Li, Feng Liu, Yanye Lu, Qiushi Ren, Liqiang Wang.“Relationship BetweeAxial Length and Retinal OxygeDynamics iAdults With Myopia” translationgal visioscience&technology , January 2025,Vol.14  No.1（2025）

2. Zi Jin, Xuhui Chen, Chunxia Jiang, Ximeng Feng, Da Zou, Yanye Lu,Jinying Li, Qiushi Ren, Chuanqing Zhou.“Predicting cognitive impairment with multimodal ophthalmic imaging and artificial neural network for community screening”. British Journal of Ophthalmology . 2024 Nov 22;108(12):1737 -1742.（2024）.

3. Hui Li, Mengdi Gao, Haiqing Song, Xiao Wu, Gang Li, Yiwei Cui, Yang Li, Zhaoheng Xie, Qiushi Ren, Haitao Zhang“ Predicting ischemic stroke risk from atrial fibrillatiobased omulti-spectral fundus images using deep learning”,Front Cardiovasc Med . 2023; 10: 1185890.（2023）

4. Jing Xiang#, LiMa, Zheng Gu, HongjuJin, HongbiZhai,Jianfei Tong,Tianjiao Liang,JuaLi, Qiushi Ren*, Qi Liu* “A Boronated Derivative of Temozolomide Showing Enhanced Efficacy iBoroNeutroCapture Therapy of Glioblastoma”, Cells, 11(7), 1173(2022).

5. Ximeng Feng, Yue Yu, Da Zou, Zi Jin, Chuanqing Zhou, GangjuLiu, James G. Fujimoto, Changhui Li, Yanye Lu, Qiushi Ren, “Functional Imaging of HumaRetina Using Integrated Multispectral and Laser Speckle Contrast Imaging,” Journal of Biophotonics  15, e202100285 (2022).

6. Zhe Jiang, Zhiyu Huang, BiQiu, Xiangxi Meng, Yunfei You, Xi Liu, Mufeng Geng, GangjuLiu, Chuanqing Zhou, KuYang, Andreas Maier, Qiushi Ren, Yanye Lu. “Weakly Supervised Deep Learning Based Optical Coherence Tomography Angiography,”  IEEE Transactions oMedical Imaging ，40 , 688-698 (2021).

7. Ximeng Feng, Da Zou, Yicheng Hu, Zhiyu Huang, Zheng Gu, Chuangqing Zhou, GangjuLiu,Qiushi Ren, Yanye Lu.“Rapid, wide-field, high quality laser speckle angiography for retinal and choroidal vessels,”  Laser Physics Letters,  18, 055601 (2021).

8. Zhiyu Huang, Zhe Jiang, Yicheng Hu, Da Zou, Yue Yu, Qiushi Ren, GangjuLiu, Yanye Lu, "Retinal choroidal vessel imaging based omulti-wavelength fundus imaging with the guidance of optical coherence tomography," Biomedical Optics Express  11, 5212-5224 (2020).

9. Zhaoheng Xie, Suying Li, KuZhou, IvaVuletic, Xiangxi Meng, Sihao Zhu, HuaXu, KuYang^*, BaixuaXu, Jinming Zhang, Qiushi Ren, “PKU-PET-II: A novel SiPM-based PET imaging system for small animals,” Nuclear Instruments & Methods IPhysics Research SectioA  877, 104-111 (2018).

10. Yanye Lu, KuYang, Kedi Zhou, Bo Pang, Guohe Wang, YicheDing, Qiushi Zhang, HongbiHan, Jiahe Tian, Changhui Li, Qiushi Ren, “AIntegrated Quad-Modality Molecular Imaging System for Small Animals,” Journal of Nuclear Medicine  743, 30-38 (2014).