Abstract：The epigenetic system helps to fulfil two basic challenges of multicellular organisms: proliferation and differentiation. Epigenetic plasticity allows cells to differentiate, whereas epigenetic inheritance and maintenance help to maintain cell fate in proliferating cells and postmitotic cells. Interestingly, epigenetic mechanism not only regulate gene expression at the current stage, but also regulates gene induction kinetics in the future, via different mechanisms in different biological processes. In this talk, I will highlight our recent discoveries regarding how epigenetic mechanisms regulate the kinetics of future gene induction in biological processes such as memory and reining.