讲座-北京大学未来技术学院

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2025.09.19

时空智能--量化生物分子时空信号的机器学习技术

摘要：近年来光学、电子显微镜、生物探针等先进生物技术的进展极大的扩展了科学家们探索生物世界的广度与深度，随之而来的是海量、复杂而又蕴含丰富信息的生物大数据。如何充分利用这些数据，做出准确、全面、自动的量化，以实现数据驱动的、可突破先验假设的科学探索，是当前生物研究的一大挑战。本报告将分享报告人近年来在应用和开发先进机...

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2025.09.18

内胚层器官的发育和再生

摘要徐成冉团队长期聚焦于哺乳动物内胚层器官的发育与再生，重点研究肝脏和胰腺谱系的分化、成熟及细胞稳态与代谢适应机制。团队结合单细胞多组学、遗传学与功能实验，系统重建了肝细胞、胰腺内分泌前体和胰岛细胞的发育谱系，解析其转录与表观遗传调控网络，并提出“内胚层器官多起源建构模式”，拓展了对器官发生过程的理解。在细胞稳态与代...

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2025.09.15

运动、神经保护与精神健康

摘要作为简便、经济、安全的非药物手段，运动能显著改善人群中的情感障碍。但我们对于运动保护脑功能和脑健康的完整机制，特别是外周“运动因子”的作用机理还不清晰。课题组近年来，围绕“运动与脑健康”这一重大问题，聚焦运动对突触可塑性调控的分子机制，取得了系列成果。特别是近期发现慢性运动可以通过调控脂肪（Cell Rep 20...

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2025.09.10

The Mismatch Repair Paradox: From Protecting the Genome to Driving Neurodegeneration

摘要： DNA mismatch repair (MMR) is renowned as a fundamental guardian of genomic stability, expertly correcting errors that arise during DNA replication. This sys...

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2025.09.09

How much do we not know about the ribosome?

摘要： The ribosome is essential for protein biosynthesis in all living organisms. Functioning as a molecular machine with extraordinary size and complexity, it tr...

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2025.08.28

Signaling roles of pyruvate kinase in pancreatic β-cells

Abstract: The ATP-generating glycolytic enzyme pyruvate kinase has been found to be a key regulator of pancreatic islet hormone secretion. This presentation wil...

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2025.08.28

Why Cilia are Cooler than You Think

Abstract: Primary cilia are long antenna-like projections found on the surface of most eukaryotic cells. Once dismissed as vestigial, these organelles are now r...

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2025.08.22

How dynamic changes in intracellular signaling shape insulin release

Abstract: Pancreatic beta cells are the only cell type in our body capable of producing and secreting the insulin necessary to absorb nutrients after a meal. Ac...

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2025.07.22

A brain switchboard for adaptive interaction with the world

Abstract：To survive in dynamic environments with uncertain resources, animals must adapt their behaviour flexibly, choosing strategies such as persevering with ...

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2025.06.16

Empowering Life Scientists with AI-Enhanced Microscopy Image Processing Tools

Abstract: Artificial intelligence (AI) is revolutionizing the field of microscopy, offering unprecedented speed, accuracy, and scalability in image processing w...

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