Abstract:
Optical coherence tomography (OCT) is an emerging medical imaging technology that uses coherent interference of broadband light to generate high-resolution (micron-scale) cross-sectional images of tissue microstructure. We have recently enhanced conventional OCT by incorporating additional contrast mechanisms—such as static and dynamic motion contrast—to enable label-free optical microangiography (OMAG/OCTA) for visualizing microcirculatory networks. This capability to image blood flow at the capillary level is critical for numerous biomedical applications. In this talk, we will highlight the fundamental principles of OCT, the enabling technologies behind OCTA, and selected applications. Examples include dynamic blood perfusion imaging in cerebral tissue of small animals and retinal microcirculation in humans.
Biography:
Dr Wang is currently a Professor of Bioengineering and Ophthalmology at the University of Washington, where he also holds the positions of George and Martina Kren Endowed Chair in Ophthalmology Research. Dr. Wang’s current research interests span biophotonics and imaging, with a focus on applications in ophthalmology, neuroscience, dermatology, and oncology. He has authored over 600 peer-reviewed journal articles, with an h-index of 98 (according to Google Scholar). He received UW Medicine Inventor of the Year in 2023, James G Fujimoto Award and SPIE Britton Chance Award in 2024. Dr. Wang is a Fellow of Optica, SPIE, and AIMBE, and was inducted to the Washington State Academy of Sciences. Additionally, he serves as the Editor-in-Chief of Biomedical Optics Express, an Optica Publishing Group journal, and is a member of the Editorial Board for the American Journal of Ophthalmology.
