个人简介
Dr. Yifu Qiu’s research interest is to understand the biology of immunity and metabolism and to develop novel therapeutic strategies against obesity and related diseases. By taking a combination of molecular, genetic, genomic, metabolic and immunological approaches,his laboratory studies 1) immune regulation of aging; 2) immune orchestration of energy homeostasis;3) brown, beige and white fat development, function and remodeling.As a corresponding author, Dr. Qiu has published his work in prestigious journals like Immunity, Nature Immunology and Cell Metabolism.
教育背景
1996.9 – 2000.7 B.S., Bioengineering, Nanchang University
2003.9 – 2010.3 Ph.D., Biochemistry and Molecular Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
工作经历
2010.11 – 2015.10 Postdoc fellow, University of California, San Francisco
2015.11 – Present Principal investigator, Peking-Tsinghua Joint Center for Life Sciences, Peking University
2015.11 – 2021.3 Principal investigator, Institute of Molecular Medicine, Peking University
2021.4 – 2023.8 Principal investigator, College of Future Technology, Peking University
2023.9 – Present Professor, College of Future Technology, Peking University
代表性论文
1. Zhou Z, Yao J, Wu D, Huang X, Wang Y, Li X, Lu Q, Qiu Y*. (2024) Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging. Immunity, 57, 513-527.
2. Huang X, Li X, Shen H, Zhao Y, Zhou Z, Wang Y, Yao J, Xue K, Wu D*, Qiu Y*. (2023) Transcriptional repression of beige fat innervation via a YAP/TAZ-S100B axis. Nature Communications, 14(1):7102.
3. Shen H, Huang X, Zhao Y, Wu D, Xue K, Yao J, Wang Y, Tang N, Qiu Y*. (2022) The Hippo pathway links adipocyte plasticity to adipose tissue fibrosis. Nature Communications, 13(1):6030.
4. Xue K, Wu D, Wang Y, Zhao Y, Shen H, Yao J, Huang X, Li X, Zhou Z, Wang Z, Qiu Y*. (2022) The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis. Cell Metabolism, 34, 1325-1341.
5. Yao J, Wu D, Zhang C, Yan T, Zhao Y, Shen H, Xue K, Huang X, Wang Z, Qiu Y*. (2021) Macrophage IRX3 promotes diet-induced obesity and metabolic inflammation. Nature Immunology, 22, 1268-1279.
